Pharmacogenetics of antiepileptic drugs: A brief review
نویسندگان
چکیده
منابع مشابه
Pharmacogenetics and enzyme induction/inhibition properties of antiepileptic drugs.
One of the major differences between the older antiepileptic drugs (AEDs) and the newer AEDs is the potential of the older AEDs for significant interactions with other medications. Many of the drug-drug interactions involving the older AEDs are reciprocal, i.e., both drugs affect each other. In contrast, the newer AEDs have either no or limited drug interaction potential. Despite our extensive ...
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Anticonvulsants are a diverse group of pharmaceuticals used in the treatment of epileptic seizures. The goal of an anticonvulsant is to suppress the rapid and excessive firing of neurons that start a seizure. The use of current antiepileptic drugs has been questioned due to the non selectivity of the drugs and the undesirable side effects posed by them. The search for antiepileptic compounds wi...
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The favourable impact of surgery for intractable epilepsy on seizures is well documented. However, few studies have determined what changes in antiepileptic drug (AED) therapy occur following surgery. Alterations in AED blood levels in the immediate postoperative period can result in breakthrough seizures. In long term follow-up, one-third to one-half of seizure-free patients after temporal lob...
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ژورنال
عنوان ژورنال: Mental Health Clinician
سال: 2016
ISSN: 2168-9709
DOI: 10.9740/mhc.2016.01.028